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This site provides important information on the correct use of TISSEEL, ARTISS and TISSUCOL with spray application.

Life-threatening/fatal air or gas embolism has occurred with the use of spray devices employing a pressure regulator to administer fibrin sealants. These events appear to be related to the use of the spray device at higher than recommended pressures and/or in close proximity to the tissue surface.

In order to ensure optimal safe use of TISSEEL, ARTISS and TISSUCOL when the product is applied using spray application, it is important to follow the information provided on this site. Please choose your country to view more details about this safety information in your local language.

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